

SPRAVATO (ESKETAMINE)
FAST AND EFFECTIVE
SPRAVATO® works faster than other antidepressant medications. Many patient start feeling better after the first treatment.
FDA-APPROVED
SPRAVATO® is the only Ketamine product approved by the FDA for the treatment of depression and the ONLY monotherapy available that can be prescribed without an antidepressant.
COVERED BY INSURANCE
SPRAVATO® is covered by most insurance plans. We are in network with most commercial insurance as well as Medicare plans in Massachusetts.
SPRAVATO® therapy involves a series of small doses of nasal Es-Ketamine spray.
Clinical studies have found SPRAVATO® effective for depression with or without an antidepressant. The discovery of Esketamine's benefits for depression has made it one of the most sought-after medical treatments in recent times.
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Esketamine (Spravato) is a fast-acting antidepressant compared to traditional antidepressants (like SSRIs, which take weeks)
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It targets NMDA receptors, which are part of the brain’s glutamate system (different from serotonin-based drugs).
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It helps regulate mood by enhancing synaptic connections and plasticity.
The Benefits Of Es-Ketamine Therapy:
SPRAVATO® is beneficial for many people who have depression because it can improve their symptoms within hours as opposed to weeks. It also works fast - often only taking one session before patients experience relief! This doesn't mean they should stop seeing a psychiatrist or psychologist though; the initial results from some trials show how effective this treatment will be on follow-up visits too.
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There is no way to predict how any single person will respond to Es-Ketamine therapy.
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These effects may not be long-lasting and will most likely require further treatments.
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Other mental health disorders like PTSD and anxiety could be helped with Ketamine products, but so far it has only been approved by the FDA for Major Depressive Disorder.
More Information From Doctor Ujala About Spravato Treatment

FAQs About Spravato Treatment
What is SPRAVATO® indicated for?
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SPRAVATO® (esketamine) CIII Nasal Spray is indicated for the treatment of:
● Treatment-resistant depression (TRD) in adults as monotherapy or in conjunction with an oral antidepressant.
● Depressive symptoms in adults with major depressive disorder (MDD) with acute suicidal ideation or behavior in conjunction with an oral antidepressant.
How is Spravato different from IV Ketamine?
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Spravato is derived from ketamine (it is the 'S' enantiomer) and is an FDA-approved nasal spray covered by most insurance plans. IV Ketamine is a racemic mixture usually administered off-label and is often paid for out-of-pocket.
What does a typical treatment schedule look like?
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Treatment usually consists of an induction phase (twice a week for 4 weeks), followed by a maintenance phase (once a week for 4 weeks), and then continued maintenance (every week or every 2 weeks) determined by your provider.
Can I drive myself home after treatment?
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No. Because of potential side effects like sedation and dissociation, you must arrange for a ride home. You should not drive or operate heavy machinery until the next day following a restful sleep.
Does insurance cover Spravato?
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Yes, because Spravato is FDA-approved, it is covered by most major insurance providers which includes Optum, Cigna, Aetna, Harvard Pillgirm, Blue Cross Blue Shield, United Healthcare, Commonwealth Care Alliance, Mass General Brigham, Medicare.






