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Your Brain Is Built to Change: How Neuroplasticity and Spravato Work Together to Treat Depression

  • Writer: UJALA FAWAD
    UJALA FAWAD
  • May 11
  • 3 min read

Have you ever wondered how you can truly change your brain? It’s more powerful than the myth that we use only 10% of it. In fact, we use all parts of our brain, even when we are resting. One of the most amazing features of our brains is neuroplasticity, the ability to rewire and adapt itself. This natural capability helps us recover from trauma, learn new skills, and grow. At Suburban Psychiatric Specialists, we see how neuroplasticity can transform lives, especially through innovative treatments like Spravato (esketamine).


What Is Neuroplasticity?


Neuroplasticity is the brain's extraordinary ability to change and adapt based on experiences and new information.


For instance, if someone practices a musical instrument regularly, the brain creates new pathways to improve playing. Similarly, if someone works on their mental health through therapy, they can develop healthier thought patterns. In essence, as you engage in neuroplasticity, you aren’t just changing thoughts; you’re becoming a new version of yourself.


Close-up view of a human brain with highlighted neural pathways
Illustration of neuroplasticity highlighting synaptic connections

How Spravato Supports Neuroplasticity


Spravato is FDA-approved for adults with treatment-resistant depression. It acts to enhance the brain's natural plasticity effectively.


Here’s how it works:


Spravato targets NMDA receptors, leading to increased levels of glutamate—a neurotransmitter that plays a crucial role in learning and memory. This surge helps in the formation of new synapses, a process known as synaptogenesis. As a direct result, patients can break away from rigid patterns that contribute to depression.


In clinical studies, nearly 70% of patients reported relief from depressive symptoms within 24 hours of treatment. This rapid response demonstrates how Spravato can prime the brain for meaningful change.


Eye-level view of a calming treatment room designed for Spravato administration
Serene treatment space for calming experiences with Spravato

How to Activate and Support Brain Growth


While Spravato opens the door to neuroplasticity, there are several healthy habits that can amplify and sustain these changes.


Mindfulness


Mindfulness practices, such as meditation and deep breathing, can significantly reduce stress and improve your emotional health. Studies show that regular mindfulness practice can lead to a 30% decrease in anxiety and a marked improvement in emotional regulation.


Exercise


Regular exercise significantly boosts mood by releasing endorphins. Research indicates that just 30 minutes of moderate exercise a day can improve symptoms of depression in nearly 50% of individuals. Whether it’s taking a brisk walk or hitting the gym, make movement a priority.


Sleep


Quality sleep is essential for forming and maintaining new neural pathways. Adults should aim for 7 to 9 hours of sleep per night to optimize brain health. Improved sleep can enhance emotional regulation and support the changes sparked by Spravato.


Growth Mindset


An adaptive mindset means seeing failures as chances to learn. For example, a student struggling in school may view their difficulties as a hurdle to overcome rather than a permanent setback. This shift in perspective can encourage brain adaptation and foster resilience.


A New Era in Mental Health


Neuroplasticity extends beyond theory; it’s a practical approach to enhancing mental health. Utilizing Spravato alongside healthy lifestyle choices offers a holistic way to combat depression, highlighting the brain’s amazing ability to heal and evolve.


As we recognize our capacity for change and adopt practices that promote brain health, we nurture a more resilient mindset.


Incorporating neuroplasticity into treatment strategies—whether through groundbreaking medicines like Spravato or simple lifestyle adjustments—opens pathways to new possibilities and brighter futures.





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